In Siddhartha, Herman Hesse conveys a very profound message for all those who seek meaning in their lives. Though set in India, the concerns of Siddhartha are universal, expressing Hesse's general interest in the conflict between mind, body, and spirit. It is a story of a Brahmin boy who follows his heart and ventures out into the world to experience life as a pious Brahmin, a Samana, a rich merchant, a lover, and ordinary ferryman to a father - each life bringing a new awakening, bringing him closer to the truth until he is finally one with Buddha.

Tokyo resident Keiko Furukara has never fit in - neither in her family, nor in school - but when at the age of 18 she begins working at the Hiiromachi branch of national convenience store chain Smile Mart, she realizes instantly that she has found her purpose in life. Delighted to be able to exist in a place where the rules of social interaction are crystal clear (many are laid out line-by-line in the store's manual), Keiko does her best to copy the dress, mannerisms, and mode of speech of her colleagues, playing the part of a "normal" person excellently, more or less.

Ryland Grace is the sole survivor on a desperate, last-chance mission - and if he fails, humanity and the Earth itself will perish. Except that right now, he doesn't know that. He can't even remember his own name, let alone the nature of his assignment or how to complete it. All he knows is that he's been asleep for a very, very long time. And he's just been awakened to find himself millions of miles from home, with nothing but two corpses for company.

The title of this novel is a combination of two Sanskrit words, “siddha,” which is defined as “achieved,” and “artha” which is defined as “meaning” or “wealth.” The word serves as the name for the principal character, a man on a spiritual journey of self-discovery during the time of the first Buddha. Siddhartha is the son of a wealthy Brahmin family who decides to leave his home in the hopes of gaining spiritual illumination. Siddhartha is joined by his best friend Govinda.

Yayoi, a nineteen-year-old woman from a seemingly loving middle-class family, has lately been haunted by the feeling that she has forgotten something important from her childhood. Her premonition grows stronger day by day and, as if led by it, she decides to move in with her mysterious aunt, Yukino.