Like it or not, global warming is a hot topic, and it will affect the younger generation the most. So why not turn to the teacher kids like the most, Ms. Frizzle! Only the Friz can boil all the hoopla down to the scientific facts in a fun and informative way. Kids already love the Magic School Bus, and the love to do what's right by the planet. At last, a way to teach the curriculum and make an impact!

Freddy Thresher has a problem: a really, really, big problem. He's the only one in his class who hasn't lost a tooth! All of the other students in Mrs. Wushy's first grade have signed their names on the Big Tooth, and Freddy's determined to get his name on it, too. So when Max "The Meanie" Sellars calls Freddy a baby, Freddy decides he's going to lose that tooth one way or another, even if it means getting punched in the face at recess, and even bigger trouble, with Mom!

Talk about a change of plans! Ms. Frizzle and her class are on the Magic School Bus headed for a museum. They have been studying how the body turns food into energy, and now they are going to see an exhibit on the human body. Things seem fine until they stop for lunch. A strange mishap causes the bus to shrink and then be swallowed! Ms. Frizzle's class is suddenly inside a real human body!

Find out what happens when Duck drives the big red tractor through town and past the popular diner where all the locals are having lunch. 

The fieldtrip to the planetarium is foiled when the museum turns out to be closed, but Ms. Frizzle saves the day. The Magic School Bus turns into a spaceship and takes the class on a trip zooming through the atmosphere, to the Moon, and beyond! With up-to-date facts about the solar system, revised for this edition.