After the loss of her mother and her own battle with breast cancer, Joanna Teale returns to her graduate research on nesting birds in rural Illinois, determined to prove that her recent hardships have not broken her. She throws herself into her work from dusk to dawn, until her solitary routine is disrupted by the appearance of a mysterious child who shows up at her cabin barefoot and covered in bruises. The girl calls herself Ursa, and she claims to have been sent from the stars to witness five miracles.

Medical student Amy Brenner is spending the night on a locked psychiatric ward. Amy has been dreading her evening working on Ward D, the hospital’s inpatient mental health unit. There are very specific reasons why she never wanted to do this required overnight rotation. Reasons nobody can ever find out. And as the hours tick by, Amy grows increasingly convinced something terrible is happening within these tightly secured walls.

Alexis Spencer thinks she has it all figured out. Even when life gets her down, she’s never too far away from another inspirational quote to rationalize her failures and ignore all her problems. Her boyfriend breaks it off, she loses her job, her closest friends are a distant memory, and her college debt is still as high as the day she left. In typical fashion, she blames the world for her problems, including her 18-year-old self who should have just tried harder and put their life on a better track.

Tess Strebel can’t recognize her own face. She can’t recognize her home. Her bedroom is unfamiliar. And she can’t remember the handsome stranger lying next to her in bed. A stranger who claims he’s her husband. Tess reads a letter in her own handwriting, composed during a rare lucid day, explaining her life as it now exists: she was in a terrible car accident one year ago. Every morning, she wakes up unable to remember most of the last decade. Including her own wedding.

Eight-year-old orphan Beth Harmon is quiet, sullen, and by all appearances unremarkable. That is, until she plays her first game of chess. Her senses grow sharper, her thinking clearer, and for the first time in her life she feels herself fully in control. By the age of 16, she's competing for the US Open championship. But as Beth hones her skills on the professional circuit, the stakes get higher, her isolation grows more frightening, and the thought of escape becomes all the more tempting.

It’s Christmas Eve and Stella Hansen is broke. She is so broke that despite working two jobs, she can’t even afford a present for her husband on their first Christmas as man and wife. But then a mysterious storekeeper at a pawn shop offers Stella an intriguing trade. Stella wants more than anything to buy her husband the Christmas gift of his dreams. But will it come at a terrible price?

Quinn Alexander has committed an unthinkable crime. To avoid spending her life in prison, Quinn makes a run for it. She leaves behind her home, her job, and her family. She grabs her passport and heads for the northern border before the police can discover what she's done. But when an unexpected snowstorm forces her off the road, Quinn must take refuge at the broken-down, isolated Baxter Motel. The handsome and kindly owner, Nick Baxter, is only too happy to offer her a cheap room for the night. Unfortunately, the Baxter Motel isn't the quiet safe haven it seemed to be.

Sarah Morgan is a successful and powerful defense attorney in Washington D.C. At 33 years old, she is a named partner at her firm and life is going exactly how she planned. The same cannot be said for her husband, Adam. He is a struggling writer who has had little success in his career. He begins to tire of his and Sarah’s relationship as she is constantly working. Out in the secluded woods, at Adam and Sarah’s second home, Adam engages in a passionate affair with Kelly Summers. Then, one morning everything changes. Adam is arrested for Kelly’s murder.

When Leeds meets Layla, he’s convinced he’ll spend the rest of his life with her - until an unexpected attack leaves Layla fighting for her life. After weeks in the hospital, Layla recovers physically, but the emotional and mental scarring has altered the woman Leeds fell in love with. In order to put their relationship back on track, Leeds whisks Layla away to the bed-and-breakfast where they first met. Once they arrive, Layla’s behavior takes a bizarre turn. And that’s just one of many inexplicable occurrences.

Two women. An office filled with secrets. One terrible crime that can't be taken back. Dawn Schiff is strange. At least, everyone thinks so at Vixed, the nutritional supplement company where Dawn works as an accountant. She never says the right thing. She has no friends. And she is always at her desk at precisely 8:45 a.m.