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  • Episode 7: Antibiotic Drug Discovery UPLC Analysis and Challenges in Medicinal Chemistry
    2025/01/04

    In this insightful interview, Medicinal Chemist Schyler Odum discusses his work in antibiotic drug discovery and the critical role of Ultra-High Performance Liquid Chromatography (UPLC) in his research. Schyler, a fifth-year graduate student at UTHSC, shares his expertise on: The importance of antibiotic drug discovery in academic institutions How UPLC differs from HPLC and its benefits in chemical analysis Challenges in sample preparation and potential improvements The complexities of synthesizing large molecular weight antibiotics The need for increased support and funding in antibiotic research Schyler also highlights the Gordon Research Conferences as a platform for presenting antibiotic drug discovery work. This video offers valuable insights for chemistry students, researchers, and anyone interested in the future of antibiotic development. #AntibioticResearch #MedicinalChemistry #UPLC #DrugDiscovery #GraduateResearch

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    13 分
  • Episode 6: Evaporative Sample Preparation for Chromatography
    2025/01/03

    Dive into the world of sample preparation with industry expert Wade Hasenour as he shares invaluable insights on rotary evaporation, centrifugal evaporation, and freeze drying. Learn about the latest advancements, challenges, and future trends in sample prep techniques for chromatography. Discover how to choose the right method for your needs, optimize your workflow, and leverage automation for better results. Whether you're a seasoned chromatographer or just starting out, this video offers essential knowledge to enhance your sample preparation skills and achieve more reliable outcomes in your research. #Chromatography #SamplePreparation #LabTechniques #ScientificResearch #massspectrometry

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    34 分
  • Episode 5: Advancing Parenteral Nutrition Analysis - UPLC-MS Method Development for Phospholipid Quantification
    2024/12/26

    Dive into the cutting-edge world of pharmaceutical analysis with Mark Dennis Retrato, a PhD candidate at Uppsala University. In this exclusive interview, Mark shares his groundbreaking research on developing a novel UPLC-MS method for analyzing phospholipids in total parenteral nutrition (TPN) products. Key highlights: • Innovative UPLC-MS method for phospholipid quantification • Importance of nitrogen evaporation in sample preparation • Unexpected findings in phosphatidylcholine species • Implications for quality control in pharmaceutical manufacturing • Potential impact on patient care and TPN product stability Learn how this research is pushing the boundaries of analytical chemistry and contributing to improved healthcare outcomes. Whether you're a scientist, healthcare professional, or simply curious about advancements in medical technology, this interview offers valuable insights into the future of parenteral nutrition analysis. Don't forget to like, subscribe, and hit the notification bell to stay updated on the latest developments in chromatography and mass spectrometry! #UPLCMS #ParenteralNutrition #PharmaceuticalAnalysis #Chromatography #MassSpectrometry #PhDResearch

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    22 分
  • Episode 4: PFAS Research Challenges: From Sampling to LC-MS Analysis
    2024/12/22

    Join Organomation's General Manager David Oliva as he interviews Bianca Costa, a PhD researcher from the University of Southern California, about her groundbreaking work on PFAS (per- and polyfluoroalkyl substances). In this in-depth discussion, Bianca shares her experiences and insights on: • The complexities of PFAS sampling and analysis in various environmental matrices • Challenges in method development for PFAS extraction and detection • The use of advanced analytical techniques like LC-MS for PFAS research • Emerging biotechnologies for PFAS remediation and the potential for microbial transformation • Community engagement efforts to assess PFAS exposure in Southern California Discover the latest advancements in PFAS research and the interdisciplinary approach needed to tackle this widespread environmental challenge. Whether you're a researcher, environmental professional, or simply interested in cutting-edge science, this interview offers valuable insights into the world of PFAS and environmental chemistry. #PFAS #EnvironmentalChemistry #WaterQuality #AnalyticalChemistry #Chromatography #Biotechnology #USC

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    53 分
  • Episode 3: Exploring MitoNEET: Unraveling Its Role in Type 2 Diabetes, Parkinson's, and Cancer
    2024/11/21

    Join us for an interesting interview with Taylor Bias, a leading researcher in the field of mitochondrial proteins, as she discusses her groundbreaking work on mitoNEET and its implications for diseases like Type 2 Diabetes, Parkinson's Disease, and Cancer. In this engaging conversation with Organomation General Manager David Oliva, Taylor shares the challenges she faced in developing analytical methods to study mitoNEET's enzymatic activities and the pivotal role of chromatography techniques like GC-MS and HPLC in her research. Discover how chromatography is evolving in the study of complex proteins and hear about some unexpected findings that have emerged from Taylor's research. For young researchers eager to dive into interdisciplinary studies, Taylor offers valuable advice on navigating this exciting field. Additionally, she addresses common misconceptions about mitoNEET and clarifies its significant role in disease mechanisms. Don't miss this opportunity to learn from an expert about the fascinating intersection of biochemistry, disease research, and advanced analytical techniques!

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    9 分
  • Episode 2: Chromatography in Action: From PFAS Research to Sheep Welfare at UNR
    2024/11/09

    In this episode of "Concentrating on Chromatography," host David Oliva explores diverse applications of chromatography and mass spectrometry with researchers from the University of Nevada, Reno. The discussion covers a range of topics, including:

    • PFAS research and thermal destruction processes
    • Short-chain fatty acid production in gut microbiomes using GC-MS
    • Cortisol analysis in sheep wool for welfare studies using ELISA
    • The versatility of university core laboratories in supporting various research projects

    Listeners will gain insights into cutting-edge research methodologies, sample preparation techniques, and the critical role of chromatography in environmental science, microbiology, animal welfare, and beyond. This episode highlights the interdisciplinary nature of analytical chemistry and its impact on addressing real-world challenges.

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    22 分
  • Episode 1: Exploring the Environmental Impact of Tire-Derived Materials Using LC-MS MS
    2024/11/09

    In this insightful interview, David Oliva, General Manager of Organomation, sits down with Jonathan Navarro Ramos, a PhD student at the University at Buffalo, to discuss his cutting-edge research on environmental pollutants. Jonathan shares his journey in developing methods to detect tire-derived chemicals like 6PPD and 6PPD-quinone in stormwater runoff and highlights the importance of non-target analysis using high-resolution mass spectrometry (HRMS). Key Topics Covered: Research on 6PPD and its transformation into 6PPD-quinone Environmental and public health concerns surrounding tire-derived chemicals The use of LC-MS/MS in detecting pollutants in challenging matrices Sample preparation techniques, including solid-phase extraction and nitrogen blowdown with the Organomation N-EVAP Future research directions involving the chlorination of pollutants in wastewater treatment Learn More: Jonathan also shares surprising findings from his study and emphasizes the global ubiquity of tire-derived pollutants. Don't miss this engaging discussion! 👉 Follow us for more updates on environmental research, chromatography techniques, and advanced laboratory equipment. #EnvironmentalResearch #TireChemicals #LCMS #MassSpectrometry #SamplePreparation #Organomation #PollutantDetection #PhDResearch

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    16 分