In this episode of The Cryosphere Podcast, hosts Max Marty and Rebecca Ziegler sit down with Mark Woodward, founder of Wake Bio, who's applying cutting-edge AI techniques to solve one of cryonics' most fundamental challenges: developing superior cryoprotectants. With a background in AI/ML at Google Brain and Stanford, Mark explains how he's now using machine learning to rapidly explore the chemical landscape in search of compounds that can protect biological tissue during freezing without the toxicity issues that plague current solutions. He's starting with Zebrafish, but his ultimate goal is full body human reanimation. Topics Discussed: -

* How AI can accelerate cryoprotectant discovery by helping us navigate chemical combinations

* The physics of vitrification and why current cryoprotectants struggle with larger organisms

* Wake Bio's methodical approach: starting with zebrafish before progressing to mammals

* Why warming tissue needs to happen faster than cooling to prevent ice crystal formation

* The debate between biological reanimation versus mind uploading approaches

* The practical challenges of transitioning from lab settings to real-world cryopreservation

* How Wake Bio's research might eventually revolutionize organ preservation and transplantation

* Mark's ambitious five-year goal of successfully preserving adult mice and ten-year vision for human cryopreservation

Links:

* Wake Bio's Website: https://wake.bio

* Contact: mark [at] wake.bio

In this episode of The Cryosphere podcast, hosts Max Marty and Rebecca Ziegler welcome Dan Held—a serial crypto entrepreneur and Bitcoin educator with over 850,000 followers on social media. As a General Partner at Asymmetric and former Head of Marketing at Kraken, Dan brings a wealth of experience in marketing disruptive technologies. He recently spoke at the Global Cryonics Summit in Miami about how cryonics can market itself and become more mainstream.

Topics Discussed:

•Dan's journey into bitcoin and how the 2008 financial crisis reshaped his worldview.
•The role of open-mindedness in embracing new technologies
•How Dan applies the concept of “return on stress” to choose his projects
•The Japanese philosophy of Ikigai and its influence on his career decisions
•Parallels between the early adoption of crypto and the current state of cryonics
•Challenges in marketing cryonics and shifting the Overton Window
•Strategies for targeting innovators and early adopters in the cryonics space
•The potential synergy between the crypto community and cryonics enthusiasts
•Philosophical discussions on immortality and the future of human experience
•An “Overrated or Underrated” segment covering NFTs, AI existential risk, and university degrees

Plus: Max & Becca's reflections on the conversation.

Relevant Links:

• Dan Held on X: https://x.com/danheld
• Dan Held on the web: https://www.danheld.com/
•Dan Held at the GCS in Miami 2024: https://www.youtube.com/watch?v=nAmXR9bQ5cw

Note: We've recently changed the name of the podcast from The Cryonics Underground to Cryosphere Podcast. We also have a new host, Rebecca Ziegler, joining Daniel Walters and Max Marty. With that, more great episodes to come!

*(edit) We are officially sold out, but you can still add your email at the bottom of the website to get updates about future events.

In this quick update episode, Max and Daniel take a break from their usual guest format to update you on the Global Cryonics Summit in Miami this July 20th and 21st. Take a quick listen and then check out the show notes for details. If you haven't purchased your tickets yet, you can grab them at GlobalCryonicsSummit.com.

Show Notes:

The event will be taking place at Ampersand Studios. We’ve secured a discounted room rate at the nearby Arlo Wynwood Hotel (you can use this discount link, but it will only work for a limited time so use it fast). If you want to extend your discount link booking to stay over on Sunday night as well, please click on Monday the 22nd as the checkout date even though it's X'd out, as that should make it work properly.

That said, Miami is a major travel destination with many wonderful places to stay so feel free to shop around.

If you’ve purchased our Patron Pass ticket, you’ll get a separate email with your pass to our Speaker/Sponsor dinner which will be Saturday evening after the day’s events. If you have already purchased a standard ticket but would like to upgrade to a Patron Pass and join us at Saturday’s Speaker and Sponsors Dinner, please reach out to us a globalcryonicssummit@gmail.com.

Arlo Wynwood Full Link:

https://be.synxis.com/?Hotel=38349&Chain=19470&arrive=2024-07-19&depart=2024-07-21&adult=1&child=0&group=PROTO