How Doctors are Using Genetic Data to Transform Patient Care with Philip Bretsky MD PhD MPH FACP

In this episode, we're joined by Dr. Philip Bretsky, a board-certified internist from Santa Monica with expertise in epidemiology and Alzheimer's research. Dr. Bretsky discusses how precision medicine is transforming healthcare by integrating genetics, biomarkers, and lifestyle factors. He explores the challenges and opportunities in implementing this approach, the evolving role of general practitioners, and how patients can advocate for personalized care. Dr. Bretsky also shares valuable resources for both health-conscious individuals and primary care providers interested in precision medicine. Join us for insights into the future of healthcare and strategies for better disease prevention and treatment.

Dr. Philip Bretsky's Contact Information:

Philip M. Bretsky MD PhD MPH FACP

1301 20th Street, Suite 230

Santa Monica, CA 90404

TEL: 310.828.4411

FAX: 310.828.2411

Facebook:@santamonicaprimarycare

Twitter / X: @santa_care

Instagram: @santa_monica_primary_care

Web: www.drbretsky.com & www.santamonicaprimarycare.com

My monthly newsletter: https://lp.constantcontactpages.com/su/JtF9zzR

Timestamps:

03:18 – Dr. Philip Bretsky’s career path and personalized care.

09:26 – Shifting from treating to preventing disease.

12:02 – Gene-environment interactions and polygenic risk scores.

19:15 – Managing complex health problems as a general practitioner.

29:06 – Reflections on the Human Genome Project’s impact.

36:29 – Case study: Preventing coronary events.

44:17 – Advice for patients on advocating for personalized

Resources Mentioned:

Books:

• "Outlive" by Peter Attia
• "The Age of Scientific Wellness" by Leroy Hood
• "The Covenant of Water" by Abraham Verghese (fiction, but related to genetic conditions)

Podcasts/Newsletters:

• Eric Topol's substack and Twitter feed
• Peter Attia's podcast

Dr. William Stanford MD PHD FACP

Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford...