In this episode of Innovating Clinical Trials, Liam Eves and Ted Trafford explore the challenges of recruitment and enrollment in clinical trials, comparing the current approach to "packing everything but the kitchen sink." They critique the overreliance on central advertising campaigns and highlight missed opportunities to address foundational issues like protocol design, site relationships, and storytelling.

Ted advocates for simplifying protocols and creating a dedicated VP of Enrollment role to optimize trials for faster delivery without compromising data integrity. Liam emphasizes the underutilized power of storytelling, showing how a compelling narrative about a study or sponsor can transform site engagement and motivation.

The discussion concludes with a call for long-term solutions to systemic enrollment issues, moving beyond the short-term study-by-study approach. Packed with practical insights and creative ideas, this episode challenges listeners to rethink clinical trial recruitment and the importance of strong, relatable narratives in building lasting partnerships with sites and patients.

In this episode of Innovating Clinical Trials, hosts Liam Eves and Ted Trafford delve into the nuanced frameworks behind effective clinical trial delivery. Liam introduces a proprietary system he has been refining for over 17 years, which leverages four critical lenses: medical/scientific/regulatory, operational/logistics, behavioral science, and leadership. These frameworks aim to streamline trial delivery, reduce costs, and optimize outcomes.

The conversation highlights how simplifying protocols and fostering early communication with regulatory bodies like the FDA can speed up trials and save resources. The discussion also explores often-overlooked aspects like the psychological dynamics of trial teams and participants, emphasizing the importance of motivation, team structure, and tailored patient engagement.

Finally, the episode underscores the significance of strong leadership in navigating inevitable challenges and ensuring cohesive execution. Packed with insights and practical strategies, this episode offers a fresh perspective on clinical trial delivery, blending science, psychology, and operational excellence.

In this episode of Innovating Clinical Trials, hosts Liam Eves and Ted Trafford dive into the complex and often chaotic world of site startup in clinical trials. Using a creative metaphor of a horse race, they vividly illustrate the hurdles and unpredictable challenges faced during site activation, from regulatory documentation delays to contract negotiations stumbling out of the gate.

Liam and Ted explore the critical impact of poor planning, misaligned communication, and unreliable vendors on trial timelines, emphasizing how these factors can derail even the most promising studies. They also discuss actionable solutions, such as adopting more realistic startup timelines, improving communication with sites and patients, and streamlining access to necessary resources and technology.

With a mix of humor, insight, and practical advice, this episode is a must-listen for anyone looking to better understand the intricacies of site startup and how to overcome its challenges.