Can IV fentanyl use during labor actually be safe for mothers and newborns beyond six centimeters of dilation? Join us as we unpack a pivotal 1989 study and question the stereotypes surrounding fentanyl use in labor.

Our second segment tackles sensational claims about IUDs and breast cancer, as we dissect a Danish study recently published in JAMA. Listen as we unpack the methodological nuances and confounders that mainstream publications have overlooked, and explore the media's role in shaping public perception with incomplete or skewed interpretations of data.

This episode closes with an in-depth look at the biases that pervade pharmaceutical research, particularly when funding sources have a vested interest in outcomes. By examining the "sponsorship effect" and its implications on research validity, we highlight the need for rigorous, unbiased scientific inquiry. We examine the evidence for the new Pretrm Test for preterm labor risk. Learn about the challenges of implementing biomarker testing for predicting preterm births and why high-quality evidence must remain the cornerstone of clinical practice. As we celebrate our 100th episode, we discuss the need for truth and transparency in scientific research—creating a future where clinical practices are driven by reliable, evidence-based insights.

00:00:02 Navigating IV Fentanyl Use in Labor

00:07:56 Debunking Misconceptions About IUDs and Breast Cancer

00:22:17 Evaluating Biomarker Testing for Preterm Birth: The PreTRM test

00:38:50 Conflicts of Interest in Medical Research

00:45:15 Biased Influence in Medical Research

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In this episode, we discuss four tips for finding evidence based answers quickly. Then we discuss some new literature about pap smears and new guidelines regarding iron supplementation in pregnancy. We also discuss the history of corticosteroids for fetal maturity and the hype cycle in medicine.

00:00:02 Finding Evidence-Based Clinical Answers Quickly

00:13:36 Understanding Evidence-Based Clinical Practice

00:23:30 Cervical Cancer Screening During Pandemic

00:33:51 Optimal Timing for Cervical Cancer Prevention

00:40:12 Iron Supplementation in Pregnancy

00:47:13 Corticosteroids and Hype in Medicine

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In this episode, we discuss the evidence behind one layer and two layer Cesarean closures with an emphasis on inclusion of the endometrium and the risk of cesarean scar ectopics and placenta accreta spectrum disorders. Plus, we define minimally invasive surgery and trace the origin of the term and it's introduce a new concept: less invasive vs minimally invasive surgery.

00:00:02 Hysterotomy Closure Techniques in Cesarean Deliveries

00:14:46 Debunking Claims About Cesarean Techniques

00:27:20 Uterine Closure Techniques in Cesarean Deliveries

00:36:44 Defining Minimally Invasive Surgery

00:48:18 Advanced Techniques in Minimally Invasive Surgery

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