Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.

Military history often highlights successes and suggests a sense of inevitability about victory, but there is so much that can be gleaned from considering failures. Study these crucibles of history to gain a better understanding of why a civilization took - or didn't take - a particular path.

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every listener can understand. It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology - the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information.

"It doesn't take an Einstein to understand modern physics," says Professor Wolfson at the outset of these 24 lectures on what may be the most important subjects in the universe: relativity and quantum physics. Both have reputations for complexity. But the basic ideas behind them are, in fact, simple and comprehensible by anyone. These dynamic and illuminating lectures begin with a brief overview of theories of physical reality starting with Aristotle and culminating in Newtonian or "classical" physics.

In his earlier best sellers Guns, Germs and Steel and Collapse, Jared Diamond transformed our understanding of what makes civilizations rise and fall. Now, in the final audiobook in this monumental trilogy, he reveals how successful nations recover from crisis through selective change - a coping mechanism more commonly associated with personal trauma.

Data science experts Foster Provost and Tom Fawcett, Data Science for Business introduces the fundamental principles of data science, and walks you through the "data-analytic thinking" necessary for extracting useful knowledge and business value from the data you collect. This guide also helps you understand the many data-mining techniques in use today.

学校や資格試験対策で学んだ英語だけで海外のお客さまと取引をしたり、出張や駐在をしたりすることは可能でしょうか？ 答えはNoです。

A leading Democrat challenges his party to return to liberal values and evidence-based science.

Words. We use them all the time, every day, mostly without giving them much thought at all. We take for granted that they’re here at our disposal whenever we need them. But if you’ve ever wished you could communicate more effectively, words are the place to start. It’s incumbent upon you to choose the best words to accomplish your goals, because how you choose to communicate influences—well, everything! The power of communication shapes our professional goals, our relationships, and our lives—so the words we choose to use carry a great deal of power.

Understanding our humanity - the essence of who we are - is one of the deepest mysteries and biggest challenges in modern science. Why do we have bad moods? Why are we capable of having such strange dreams? How can metaphors in our language hold such sway on our actions? As we learn more about the mechanisms of human behavior through evolutionary biology, neuroscience, anthropology, and other related fields, we're discovering just how intriguing the human species is.

■人気書籍、アルク「キクタン ビジネス【Advanced】」の例文音声です!本コンテンツには、書籍に収録の全784単熟語を使った「例文」読み上げ音声(英語+日本語訳)が収録されています。■単熟語は分野別に整理されているので、自分の仕事とも関連づけやすい!(経済・景気/仕事・人材/製造・製品/販売・流通/金融・不動産/IT・通信/法律・税制/その他)※本コンテンツにテキスト情報は含まれておりません。書籍と合わせて学習することをおすすめ致します。■対象レベル:全レベル

Eating is an indispensable human activity. As a result, whether we realize it or not, the drive to obtain food has been a major catalyst across all of history, from prehistoric times to the present. Epicure Jean-Anthelme Brillat-Savarin said it best: "Gastronomy governs the whole life of man."

Language defines us as a species, placing humans head and shoulders above even the most proficient animal communicators. But it also beguiles us with its endless mysteries, allowing us to ponder why different languages emerged, why there isn't simply a single language, how languages change over time and whether that's good or bad, and how languages die out and become extinct.

Grammar! For many of us, the word triggers memories of finger-wagging schoolteachers, and of wrestling with the ambiguous and complicated rules of using formal language. But what is grammar? In fact, it's the integral basis of how we speak and write. As such, a refined awareness of grammar opens a world of possibilities for both your pleasure in the English language and your skill in using it, in both speech and the written word.

What is our species' greatest invention? Medicine, computers, space travel? Not even close. The innovation that underlies each of our past achievements and those we still aspire to is language. Language is the ultimate invention of Homo sapiens - one that has allowed us to change the physical and social world around us in every conceivable way, and an invention that has fundamentally changed us, as well.

With all the advances in science in the last century, why are there still so many infectious diseases? Why haven’t we found cures for difficult cancers? Why hasn’t any major progress been made in the treatment of mental illness? And how do we intend to stop, and not only that but reverse, global warming and the climate crisis? In Saved by Science, scientist Mark Poznansky examines the many crises facing humanity while encouraging us with the promise of an emerging solution: synthetic biology.

Faced with the ceaseless stream of news about war, crime, and terrorism, one could easily think we live in the most violent age ever seen. Yet as New York Times bestselling author Steven Pinker shows in this startling and engaging new work, just the opposite is true: violence has been diminishing for millennia and we may be living in the most peaceful time in our species's existence.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

Join three literary scholars and award-winning professors as they introduce you to dozens of short masterpieces that you can finish - and engage with - in a day or less. Perfect for people with busy lives who still want to discover-or rediscover-just how transformative an act of reading can be, these 36 lectures range from short stories of fewer than 10 pages to novellas and novels of around 200 pages. Despite their short length, these works are powerful examinations of the same subjects and themes that longer "great books" discuss.

「ビジネスシーンでネイティブの会話を聞き取れるようになりたい」「英語で自然に会話できるようになりたい」という方のためのトレーニングブック。

北海道西南部、上ノ国町の海を望む山の頂に、夷王山神社（いおうざんじんじゃ）が建つ。その中腹には、保存状態の良い、中世の山城・勝山館（かつやまだて）の遺跡がある。中世、北海道の南部には「渡党（わたりとう）」と呼ばれる、和人もしくは人種的・文化的に和人に近いアイヌが住んでいた。彼らは「道南十二館」と呼ばれる拠点を築き、各館は道南、津軽、秋田にかけての地域を支配した豪族・安東氏の配下にあった。「上ノ国」という地名も、二家に分かれた安東氏の家名に由来する。渡党はアイヌと本州との交易などを糧としていたが、やがてアイヌとの摩擦が拡大、渡島半島東部の首長・コシャマインを中心とするアイヌの蜂起に発展する。アイヌは強く、十二館のうち十までが陥落する。そこで、上ノ国・花沢館の館主・蠣崎氏（かきざきし）の養子となっていた、若狭武田氏の一族という武田信広が、残った武士を集めて反撃、アイヌに勝利する。戦いの後、花沢館は勝山館に移り、信広は夷王山山頂に葬られたという。その子孫は蝦夷地での支配権を確立、安東氏の支配をも脱して、松前藩主・松前氏となる。夷王山は、松前氏にとって、偉大な祖神が眠る聖地であった。神社を鍵に、知られざる中世北海道の歴史を紐解く。

NYタイムズベストセラーをオーディオ化！！
すべてのオナラをしたことのある人へ送る、80種の生き物のオナラについて科学的に考察した、ユーモアあふれる究極の生き物事典

Six days ago, astronaut Mark Watney became one of the first people to walk on Mars. Now, he's sure he'll be the first person to die there. After a dust storm nearly kills him and forces his crew to evacuate while thinking him dead, Mark finds himself stranded and completely alone with no way to even signal Earth that he’s alive - and even if he could get word out, his supplies would be gone long before a rescue could arrive. But Mark isn't ready to give up yet.