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  • Mpox Treatment Strategies, Clinical Presentation, and Diagnostic Approaches
    2024/11/19

    Mpox is an evolving global health threat, and clinicians should be aware of characteristic signs and symptoms to ensure timely diagnosis and appropriate management. Author Jason Zucker, MD, MS, of Columbia University Irving Medical Center speaks with JAMA Deputy Editor Preeti Malani, MD, MSJ, about the transmission, diagnosis, management, and prevention of mpox.

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    • Mpox Clinical Presentation, Diagnostic Approaches, and Treatment Strategies
    • The Resurgence of Mpox in Africa
    • Decline of Mpox Antibody Responses After Modified Vaccinia Ankara–Bavarian Nordic Vaccination
    • WHO Announces Mpox Global Plan, Appeals for Funding
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    17 分
  • Calcific Aortic Stenosis: Symptoms, Diagnosis, and Treatment
    2024/11/11

    Calcific aortic stenosis affects approximately 12% of people >75 years in the US and worldwide leads to more than 100 000 deaths each year. Catherine M. Otto, MD, PhD, of the University of Washington School of Medicine, Seattle, discusses the symptoms, diagnosis, and treatment of aortic stenosis with JAMA Deputy Editor Kristin L. Walter, MD, MS.

    Related Content:

    • Calcific Aortic Stenosis
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    19 分
  • CAR T Cells and T-Cell Therapies for Cancer
    2024/11/04

    CAR T cells are genetically engineered to express a receptor that recognizes and kills tumor cells. CAR T-cell products are now FDA approved for 6 hematologic malignancies. Author Jennifer N. Brudno, MD, National Cancer Institute, joins JAMA Deputy Editor Mary McGrae McDermott, MD, to discuss "CAR T Cells and T-Cell Therapies for Cancer: A Translational Science Review.”

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    • CAR T Cells and T-Cell Therapies for Cancer
    • Translational Science Reviews—A New JAMA Review
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    18 分
  • Diagnosis and Treatment of Peptic Ulcer Disease
    2024/10/28

    Peptic ulcer disease affects approximately 1% of the population in the US, and H pylori is a common cause of peptic ulcer disease. Author Nimish Vakil, MD, a gastroenterologist from the University of Wisconsin, Madison, discusses current evidence regarding diagnosis and treatment of peptic ulcer disease with JAMA Deputy Editor Mary McGrae McDermott, MD.

    Related Content:

    • Peptic Ulcer Disease
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    22 分
  • Strategies for Helping Patients Navigate High Prescription Drug Costs
    2024/10/21

    High prescription costs are a major barrier to the optimal treatment of many health conditions. Prescribers need tools to help patients find the lowest drug costs. Author Hussain S. Lalani, MD, MPH, MSc, of Brigham and Women's Hospital and Harvard Medical School joins JAMA Senior Editor Anne R. Cappola, MD, ScM, to discuss "Strategies to Help Patients Navigate High Prescription Drug Costs."

    Related Content:

    • Strategies to Help Patients Navigate High Prescription Drug Costs
    • Strategies to Help Patients Afford Their Medicines in the US
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    13 分
  • Preexposure Prophylaxis (PrEP) Options for HIV
    2024/10/14

    Even though highly effective medications are currently available to prevent HIV, there are about 1.3 million new infections worldwide each year. Monica Gandhi, MD, MPH, of the University of California San Francisco joins JAMA Senior Editor Karen E. Lasser, MD, MPH, to discuss preexposure prophylaxis (PrEP) for HIV.

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    • Preexposure Prophylaxis (PrEP) for HIV
    • What Is Doxycycline Postexposure Prophylaxis?
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    14 分
  • Update on Over-the-Counter (OTC) Contraception
    2024/10/09

    In July 2023, the US Food and Drug Administration (FDA) approved Opill, a daily progestin-only oral contraceptive for over-the-counter sale to people of all ages. Daniel Grossman, MD, discusses this and more with JAMA Associate Editor Melissa A. Simon, MD, MPH.

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    • Over-the-Counter Oral Contraceptives
    • Over-the-Counter Oral Contraceptive Pills
    • Over-the-Counter Progestin-Only Oral Contraceptives
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    13 分
  • Dialysis for Chronic Kidney Failure
    2024/10/02

    Selection of hemodialysis or peritoneal dialysis and timing of dialysis initiation are influenced by patient symptoms, laboratory trajectories, patient preferences, and therapy cost and availability; shared decision-making is key. Jennifer E. Flythe, MD, MPH, from the University of North Carolina, discusses dialysis for chronic kidney failure with JAMA Deputy Editor Kristin L. Walter, MD, MS.

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    • Dialysis for Chronic Kidney Failure
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    22 分