Episode 21 of the Performance Around the Clock podcast comes from the 2024 Society for Research on Biology Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. This week’s guest is Dr. Achim Kramer who developed an assay (BodyTime) to determine internal circadian time. He talks about the development of the assay and how it can be used in circadian medicine. Dr. Kramer is Head of Chronobiology at Charité – Universitätsmedizin Berlin, the largest research hospital in Europe. Thank you for listening.

Guest:

Dr. Achim Kramer

Head of Chronobiology at Charité – Universitätsmedizin Berlin

Lab website:

https://www.achim-kramer-lab.de/

Body clock test:

https://www.bodyclock.health/

BodyTime

High-accuracy determination of internal circadian time from a single blood sample

https://pubmed.ncbi.nlm.nih.gov/29953415/

Host:

Dr. Satchin Panda

@SatchinPanda

https://x.com/SatchinPanda

Instagram: @satchin.panda

https://www.instagram.com/satchin.panda/

Links:

Donations: https://panda.salk.edu/giving/

Research: https://www.salk.edu/scientist/satchidananda-panda/

More science: https://mycircadianclock.org/

Performance Around the Clock episode 20 comes from the 2024 Society for Research on Biology Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. We have the pleasure to talk with Dr. Christoph Scheiermann who studies the role of circadian rhythms in immune response and how this impacts health and disease. In particular, he’s known for his research on the recruitment and localization of leukocytes which is under circadian control. This process plays a crucial role in immune response which can be leveraged to improve cancer immunotherapy and vaccination efficacy. Learn more about his impactful research in this episode. Thanks for listening.

Guest:

Dr. Christoph Scheiermann

Full Professor

Department of Pathology and Immunology

Centre Medical Universitaire (CMU)

X (formerly Twitter): @ScheiermannLab

https://twitter.com/ScheiermannLab

Lab webpage:

http://scheiermannlab.de/

Host:

Dr. Satchin Panda

@SatchinPanda

https://x.com/SatchinPanda

Instagram: @satchin.panda

https://www.instagram.com/satchin.panda/

Episode 19 of the Performance Around the Clock podcast comes from the 2024 Society for Research on Biological Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. We have the honor to talk with one of the pillars of the circadian field - Dr. Joseph Takahashi. Dr. Takahashi pioneered the use of forward genetics and positional cloning in mouse as a tool to discover genes that underlie neurobiology and behavior. His discovery of clock genes led to a description of a conserved circadian clock mechanism in animals. In this podcast, we hear about how his lab discovered and cloned the mouse circadian Clock gene. In addition, we find out how circadian alignment of feeding, daily fasting and caloric restriction can combine to increase longevity.

Dr. Takahashi has authored more than 300+ scientific publications and the recipient of many awards and distinctions including:

The Honma Prize in Biological Rhythms Research

NSF Presidential Young Investigator Award

Searle Scholars Award

Bristol-Myers Squibb Unrestricted Grant in Neuroscience, and the C. U. Ariens Kappers Medal. W. Alden Spencer Award in Neuroscience from Columbia University

Fellow of the American Academy of Arts and Sciences

Member of the National Academy of Sciences

Member of the National Academy of Medicine

Gruber Neuroscience Prize at the Society for Neuroscience

Guest:

Dr. Joseph Takahashi

Chair of the Department of Neuroscience at UT Southwestern Medical Center

Loyd B. Sands Distinguished Chair in Neuroscience

X (formerly Twitter): @CircadianClocks

https://twitter.com/circadianclocks

UT Southwestern profile:

https://profiles.utsouthwestern.edu/profile/105885/joseph-takahashi.html

Lab webpage:

https://labs.utsouthwestern.edu/takahashi-lab

Host:

Dr. Satchin Panda

@SatchinPanda

https://x.com/SatchinPanda

Instagram: @satchin.panda

https://www.instagram.com/satchin.panda/

Links:

Donations: https://panda.salk.edu/giving/

Research: https://www.salk.edu/scientist/satchidananda-panda/

More science: https://mycircadianclock.org/

Episode 18, the final episode from the Cell Symposia meeting on Exercise Metabolism in Lisbon, features Dr. Bret Goodpaster. As the Scientific Director at AdventHealth's Translational Research Institute, Dr. Goodpaster is a leading expert in exercise physiology and metabolism. In this episode, he shares his insights on exercise, muscle, aging, and the athlete’s paradox. We also delve into two major scientific projects - HealthABC (Health, Aging Body and Composition) and MoTrPAC (Molecular Transducers of Physical Activity Consortium). HealthABC explores risk factors for functional decline in older adults, including muscle aging. MoTrPAC is a large consortium created to understand the molecular mechanisms of physical activity on health benefits. We hope you will find this episode intellectually stimulating. Thank you for listening.

Guest: Dr. Bret Goodpaster

Scientific Director at Advent Health’s Translational Research Institute

https://www.adventhealthresearchinstitute.com/team/bret-goodpaster

Host: Dr. Satchin Panda

X (formerly Twitter): @SatchinPanda

https://x.com/SatchinPanda

Instagram: @satchin.panda

https://www.instagram.com/satchin.panda/

Links:

Donations: https://panda.salk.edu/giving/

Research: https://www.salk.edu/scientist/satchidananda-panda/

More science: https://mycircadianclock.org/

Episode 17 of the Performance Around The Clock podcast comes from the Cell Symposia meeting on Exercise Metabolism in Lisbon. We were honored to host Dr. Bente Klarlund Pedersen and to talk about her brilliant career from her seminal research on myokines to "exercise as medicine". Dr. Pedersen also tells us about how she uses her knowledge of exercise to educate the public and effect policy changes. Guest: Dr. Bente Klarlund Pedersen Director of Centre for Physical Activity Research (CFAS) https://www.inflammation-metabolism.dk/ X (formerly Twitter): @benteklarlundp https://x.com/benteklarlundp Host: Dr. Satchin Panda X (formerly Twitter): @SatchinPanda https://x.com/SatchinPanda Instagram: @satchin.panda https://www.instagram.com/satchin.panda/ Links: Donations: https://panda.salk.edu/giving/ Research: https://www.salk.edu/scientist/satchidananda-panda/ More science: https://mycircadianclock.org/

Episode 16 of the Performance Around the Clock podcast comes from the Cell Symposium on Exercise Metabolism in Lisbon, Portugal and features Dr. Mark Febbraio who is the head of Cellular and Molecular Metabolism Laboratory at Monash Institute of Pharmaceutical Sciences. His research focuses on understanding mechanisms associated with exercise, obesity, type 2 diabetes and cancer with an aim towards developing novel drugs to treat lifestyle related diseases. In this episode, we hear about how he transitioned from a triathlete into a researcher in exercise science. We also learn about the link between exercise and inflammation and leveraging this knowledge to treat disease. Enjoy!

Guest:

Dr. Mark Febbraio

Professor, Drug Discovery Biology

Cellular and Molecular Metabolism Laboratory

Monash Institute of Pharmaceutical Sciences

X (formerly Twitter): @FebbraioMark

https://twitter.com/FebbraioMark

Host:

Dr. Satchin Panda

X (formerly Twitter): @SatchinPanda

https://twitter.com/SatchinPanda

Instagram: @satchin.panda

https://www.instagram.com/satchin.panda/

Links:

Donations: https://panda.salk.edu/giving/

Research: https://www.salk.edu/scientist/satchidananda-panda/

More science: https://mycircadianclock.org/

This week’s episode of the Performance Around the Clock podcast (episode 15) comes from the Cell Symposium on Exercise Metabolism in Lisbon, Portugal. Dr. Amber Mueller, scientific editor at Cell Metabolism and co-organizer of the symposium talks to us about life as a scientific editor and about the field of exercise metabolism. Enjoy!

Guest:

Dr. Amber Mueller

Scientific Editor at Cell Metabolism

X (formerly Twitter): @AmberMuellerPhD

https://twitter.com/AmberMuellerPhD

Host:

Dr. Satchin Panda

X (formerly Twitter): @SatchinPanda

https://twitter.com/SatchinPanda

Instagram: @satchin.panda

https://www.instagram.com/satchin.panda/

Links:

Donations: https://panda.salk.edu/giving/

Research: hhttps://www.salk.edu/scientist/satchidananda-panda/

More science: https://mycircadianclock.org/

In episode 14 of the Performance Around the Clock podcast, Dr. Laura van Rosmalen, a WuTsai scholar and postdoctoral researcher at the Salk Institute joins us to talk about her work with voles and seasonal rhythms, diurnality, nocturnality and energy balance, and a surprising connection with RED-S (Relative Energy Deficiency in Sport). Enjoy!

Guest:

Dr. Laura van Rosmalen

WuTsai scholar

Salk Institute for Biological Studies

X (formerly Twitter): @RosmalenLaura

https://twitter.com/RosmalenLaura

Host:

Dr. Satchin Panda

X (formerly Twitter): @SatchinPanda

https://twitter.com/SatchinPanda

Instagram: @satchin.panda

https://www.instagram.com/satchin.panda/

Links:

Donations: https://panda.salk.edu/giving/

Research: https://www.salk.edu/scientist/satchidananda-panda/

More science: https://mycircadianclock.org/