In something of a bonus episode, Gavin, Richard, and Jessamy sit down for an informal chat about what's going on in the news, in health, and in the world of The Lancet, covering healthcare emissions, solar power, and the challenge of global co-operation on vaccines.

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The mpox case surge in Africa has been declared a Public Health Emergency of International Concern (PHEIC) by the WHO. A new clade of the virus has emerged since the 2022 outbreak which has led to a rapid increase in cases. Professor Salim Abdool Karim, who is the the chair of the Africa CDC’s Emergency Consultative Group and the director of CAPRISA, the Center for the AIDS Programme of Research in South Africa, joins Gavin Cleaver and Maneet Virdi to lay out in clear terms what's happening in Africa, what the PHEIC means, and what the future could look like.

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The first module of the UK's COVID-19 enquiry was published in July 2024. The enquiry found that the UK prepared for the wrong sort of pandemic, suffered from groupthink, and ultimately failed its citizens, more than 200,000 of whom died as a result of the pandemic.

Editor-in-chief of The Lancet, Richard Horton, joins Gavin and Jessamy to discuss his experiences giving evidence to the enquiry. We reflect on the findings, dissect their meaning for pandemic preparedness, and talk about what the UK government needs to do next.

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14 modifiable risk factors account for 45% of dementia cases worldwide. Gavin and Jessamy are joined by Prof. Gill Livingston (UCL) and Prof. Geir Selbaek (University of Oslo) to discuss the 2024 updates to The Lancet Commission on dementia prevention.

You can read the Commission here:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01296-0?dgcid=buzzsprout_tlv_podcast_generic_lancet

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Gavin and Jessamy are joined by Mandeep Dhaliwal, Director of UNDP’s HIV, Health and Development Group, to discuss the access to health and freedom of the most vulnerable people around the world. Are we maintaining progress on rights, or are we in danger of backsliding?

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Gavin and Jessamy are joined by Oksana Pyzik (UCL, Fight The Fakes Alliance) to discuss how Ozempic/Wegovy/semaglutide works, what becoming mainstream means for our understanding of obesity and public health, and how demand is fuelling an unregulated black market in the drugs.

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Anita Zaidi, President of The Gender Equality Division at the Gates Foundation, joins Gavin to discuss women in global health from visibility in data all the way through to women in leadership positions in global health. Also on the agenda is the impact of vaccines, innovations in gender equity, and challenges and successes in addressing maternal mortality.

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Gavin and Jessamy are joined by Rupa Sarkar, editor-in-chief of The Lancet Digital Health, to discuss the uses of Large Language Models (LLMs) in healthcare, the safety and patient concerns, progress that’s been made, and the what the future of AI in health might hold.

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