James Peyer is the CEO and founder of Cambrian Bio, a company that develops therapeutics targeting key biological pathways that decline or malfunction with age to create medicines that have the potential to treat and prevent some of today's most debilitating diseases.

Cambrian is viewed as one of the most exciting biotech companies around, raising $160m in the last 5 years.

Brought to you by TAV, James joins Jack and Rich to discuss his personal journey, longevity, Cambrian's journey to human trials, regulatory considerations and so much more.

Chris Tottman was part of the founding team at MessageLabs, a cybersecurity startup offering email scanning for viruses and spam which grew from £0-£150m in ARR in 7 years, being acquired by Symantec for $695m.

The day after the acquisition announcement, the founding team formed Notion Capital where Chris is a Founding Partner. Notion is one of the first true operator led VC firms in Europe with €1.2bn AUM having backed the likes of GoCardless, Paddle, CurrencyCloud, Mews and more.

Brought to you by TAV, Chris joins Jack and Rich to discuss his journey, the GTM motions of MessageLabs, implementing a good culture when hyperscaling, what makes a good investor, board experience and so much more.

Markus Fuhrmann is a serial entrepreneur founding Delivery Hero, the global food delivery platform that's transformed how people order and receive meals. DeliveryHero is a company with a $6bn market cap today, operating in over 50 countries and partnering with hundreds of thousands of restaurants worldwide.

Beyond Delivery Hero, Markus is also a founding partner at Cavalry and Bitkraft Ventures, early stage venture firms focusing on enterprise and gaming respectively.

He’s also now the founder of Gropyus, a proposition that streamlines housing construction.

Brought to you by TAV, Markus joins Jack and Rich to discuss his journey, the buy and build model, quick commerce today and making the switch from operator to investor, and then back again.

Dan Chaplin is a Partner at Dawn Capital.

Dawn Capital is one of Europe’s leading specialist B2B software investors, announcing a $700m fund in September 2023 to invest in the next generation of global software leaders.

Dan leads on all things fintech with a particular interest in payments, credit, digital assets and infrastructure platforms and has subsequently led on investments including open banking leader Tink, digital assets infrastructure platform Copper, as well as Cover Genius, Elwood, Billie, Access Fintech and OpenGamma.

This episode really drills into fintech where we discuss:

• Whether it's becoming more of a value sector
• Whether Dan prefers products that have broad market appeal at low margins, vs those narrower market appeal and much higher margins
• Profitability expectations
• Unit economics across a company’s lifecycle
• Fragmentation across the US and Europe
• Regulation
• Board learnings

Ertan Can is the Founder of Multiple Capital.

Multiple Capital invests in micro and seed-stage venture capital funds globally with a focus on European managers, frequently solo fund managers in niche geographies and verticals that are often overlooked.

The firm has backed Nathan Beniach’s Air Street Capital, which recently raised its second fund of $121m and Angular Ventures, the deep tech fund backing companies out of Tel Aviv and London.

Subsequently, their euros have been invested into category-defining companies such as UiPath and Sorare, $43bn and $4.3bn enterprise value companies respectively.

We discuss:

• What is an 'emerging manager' and when does a manager move from emerging to established?
• Preferred portfolio construction
• Why does backing emerging managers matter when venture tends to favour those who have already been successful?
• What does an investable / great emerging manager look like?
• What signs does Ertan look out for to decide when to stop investing in an emerging manager?
• The different challenges a manager has to face as he/she moves from 1st fund to 2nd fund to 3rd fund and so on
• The parallels between emerging/established GPs and emerging/established LPs

Marc Cohen is a Solo GP at unbundled vc.

unbundled is a single FO deal-by-deal vehicle that co-invests 50-200k alongside leading VCs into early-stage digital tech companies and has backed the likes of Magrathea and Runna.

We discuss:

• Founder or market in early-stage investing
• The switch from algorithmic trading to VC
• The investments of Runna and Magrathea
• Is it best to be ownership-sensitive or sensible?
• Why a fund is the natural next step, LP strategy and points of differentiation
• Portfolio construction

Laura McGinnis is an investor at Balderton Capital.

Balderton is a tier-one venture capital firm that has been investing in Europe for more than 20 years backing companies like Revolut, Depop, Dream Games, Contentful and The Hut Group, spurred by two funds, early and growth, and the ability to write checks up to $60M.

Laura focuses her time on early-stage Retail, Climate, Cyber Security, and Crypto investments and is passionate about youth education and wealth equity having previously worked as an early consultant for The Fifteen Percent Pledge, a non-profit organisation creating sustainable ecosystems for Black-owned businesses.

We discuss:

• Getting airtime for consumer at Balderton
• What characterises one of the world's leading VC funds
• Forming defensibility around consumer propositions
• How operational experience has improved Laura’s outlook on being an investor
• The ideal marketing mix for consumer propositions
• Diversity in VC & entrepreneurship. What needs to change

This week's guests are Dan Marcus, CEO at Ramp and Paul Lehair, Investment Director at Albion VC.

Ramp is a UK-based predictive analytics start-up. The team provide executive and FP&A teams with valuable insights and accurate forecasts to make informed, data-driven decisions boasting a customer base that includes major players like FRVR, Pixel, and Space Ape Games. Albion led Ramp's $5m seed round in March this year with Eurazeo & Triple Point.

We discuss:

• Dan’s journey before forecasting
• Paul’s value add of being a seasoned operator in VC
• Turning forecasting into a science rather than an art; driving an environment which is 100% data-driven
• Why every fintech investor is also an AI investor
• Proving out the product in gaming before moving on to other sectors
• Building a business in South Africa; a 101 on how to navigate the talent pool
• Dealing with founders who are overly bullish and optimistic from a runway and cash perspective